Insight into peculiar adhesion of cells to plasma‐chemically prepared multifunctional “amino‐glue” surfaces

نویسندگان

چکیده

Plasma polymers (PPs) can easily modify material surfaces to improve their bio-applicability due match-made surface-free energy and functionality. However, cell adhesion PPs typically composed of various functional groups has not yet been fully understood. We explain the origin strong resistance trypsin treatment previously noted for nonendothelial cells on amine PPs. It is caused mainly by nonspecific negatively charged parts transmembrane proteins positively PP surface, enabled thin glycocalyx. endothelial are bound primarily thick, glycocalyx sporadically integrins in kinetic traps, both cleaved trypsin. Cell scratching atomic force microscopy tip confirmed correlation strength adhesion.

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ژورنال

عنوان ژورنال: Plasma Processes and Polymers

سال: 2023

ISSN: ['1612-8869', '1612-8850']

DOI: https://doi.org/10.1002/ppap.202200157